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Etolorex

From Wikipedia, the free encyclopedia
Etolorex
Skeletal formula
Ball-and-stick model of etolorex
Clinical data
Routes of
administration
Oral
ATC code
  • none
Legal status
Legal status
  • In general: uncontrolled
Identifiers
  • 2-{[1-(4-chlorophenyl)-2-methylpropan-2-yl]amino}ethanol
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC12H18ClNO
Molar mass227.73 g·mol−1
3D model (JSmol)
  • Clc1ccc(cc1)CC(NCCO)(C)C

Etolorex is a central nervous system (CNS) stimulant and anorectic drug belonging to the substituted amphetamine and phenethylamine chemical classes. Etolorex was derived from phentermine, an amphetamine derivative in its own right frequently prescribed as a weight loss drug for the treatment of obesity with a positive side effect of CNS activation and energizing the patient.[1][2] Etolorex, for unknown reasons, was never marketed.[1]

Synthesis

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Patent:[3]

Made by the reaction of chlorphentermine with 2-Chloroethanol.

See also

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References

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  1. ^ a b Triggle DJ (1996). Dictionary of Pharmacological Agents. Boca Raton: Chapman & Hall/CRC. ISBN 0-412-46630-9.
  2. ^ "The use of common stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances" (PDF). Retrieved 2010-03-24.[dead link]
  3. ^ BE615731 (1962) idem GB 959958  (1964 to Degussa).