Draft:Onder Albayram
Submission declined on 2 February 2025 by Significa liberdade (talk).
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| Submission declined on 29 July 2024 by Asilvering (talk). This draft's references do not show that the subject qualifies for a Wikipedia article. In summary, the draft needs to Declined by Asilvering 7 months ago.
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Onder Albayram | |
|---|---|
| Born | March 12, 1980 Gaziantep, Turkey |
| Nationality | Turkish, American |
| Alma mater | University of Southern California (MSc), Bonn University (PhD) |
| Known for | Traumatic Brain Injury and Dementia |
| Scientific career | |
| Fields | Neuroscience, Neuropharmacology, Molecular Biology |
| Institutions | MRC Laboratory of Molecular Biology, University of Southern California, Bonn University, Harvard Medical School, Medical University of South Carolina |
| Doctoral advisor | Andreas Zimmer |
| Website | https://education.musc.edu/muscapps/facultydirectory/Albayram-Onder |
Onder Albayram (born March 12, 1980) is a Turkish-American neuroscientist and neuropharmacologist[1]. He is an Assistant Professor of Pathology and Neuroscience at the Medical University of South Carolina in Charleston, USA[2]. His research focuses on interdisciplinary approaches integrating his background and research interests in aging brain and dementia. Dr. Albayram's laboratory studies the different involvement of innate neuroprotective mechanisms in the physiology of young and aged brains, as well as pathological conditions relevant to cerebrovascular[3][4] and trauma-related disorders[5][6].
Education and Career
[edit]His journey into the realm of research training commenced during his undergraduate years at the MRC Laboratory of Molecular Biology, University of Cambridge, Cambridge, UK[7]. In 2008, he completed his master's in pharmaceutical sciences at the University of Southern California, Los Angeles, USA.
In 2009, he joined the Institute of Molecular Psychiatry Ph.D. program at the University of Bonn in Germany. His research focused on the molecular and cellular mechanisms of age-dependent changes in the endocannabinoid system and their effects on long-lasting neuro-immune adaptations. This research led to the discovery of the crucial role of Cannabinoid-1 receptor-expressed GABAergic neurons in regulating microglial activity and its protective function in aging brain[8][9][10]. Albayram also equally contributed to the discovery that low doses of Δ9-tetrahydrocannabinol (THC) appeared to rejuvenate aged brains by restoring deficits in cannabinoid signaling, contrary to its documented detrimental effects in young brains[11]. This finding was published as a cover story in Nature Medicine and has been recognized by numerous press outlets, including Inverse[12] and Alzheimer's Association Forum[13].
After completing his research training in neurobiology related to brain aging in Europe, Dr. Albayram joined Harvard Medical School in 2014, which developed novel tests to identify a specific form of the phosphorylated axonal protein tau (cis P-tau) as a precursor to traumatic brain injury (TBI) and related-dementia[14].
References
[edit]- ^ Öz, Esra (2017-11-14). "Bilim dünyasının çılgın nörobilimcisi -". CNN TÜRK (in Turkish). Retrieved 2025-03-14.
- ^ "Onder Albayram Academic Profile". Medical University of South Carolina. Retrieved 2025-01-20.
- ^ "A first glimpse of the human brain's drains". EurekAlert!. Retrieved 2025-03-08.
- ^ mkwildeman@postandcourier.com, Mary Katherine Wildeman (2021-07-05). "MUSC, Harvard research shows promise in Alzheimer's and dementia treatment". Post and Courier. Retrieved 2025-03-08.
- ^ "Discovery of a natural protective response in the brain could lead to treatments for concussions". EurekAlert!. Retrieved 2025-03-08.
- ^ "New compound shows early promise for treatment of Lou Gehrig's disease in preclinical models". EurekAlert!. Retrieved 2025-03-08.
- ^ Cheung, Benny H. H.; Cohen, Merav; Rogers, Candida; Albayram, Onder; de Bono, Mario (2005-05-24). "Experience-Dependent Modulation of C. elegans Behavior by Ambient Oxygen". Current Biology. 15 (10): 905–917. Bibcode:2005CBio...15..905C. doi:10.1016/j.cub.2005.04.017. ISSN 0960-9822. PMID 15916947.
- ^ Albayram, Onder; Alferink, Judith; Pitsch, Julika; Piyanova, Anastasia; Neitzert, Kim; Poppensieker, Karola; Mauer, Daniela; Michel, Kerstin; Legler, Anne; Becker, Albert; Monory, Krisztina; Lutz, Beat; Zimmer, Andreas; Bilkei-Gorzo, Andras (2011-07-05). "Role of CB1 cannabinoid receptors on GABAergic neurons in brain aging". Proceedings of the National Academy of Sciences. 108 (27): 11256–11261. Bibcode:2011PNAS..10811256A. doi:10.1073/pnas.1016442108. PMC 3131310. PMID 21690345.
- ^ Byrne, Michael (2011-07-12). "How Eternal Mental Youth Relates To Hash". VICE. Retrieved 2025-02-06.
- ^ "Bodyguard for the brain: Researchers identify mechanism that seems to protect brain from aging". ScienceDaily. Retrieved 2025-02-06.
- ^ Bilkei-Gorzo, Andras; Albayram, Onder; Draffehn, Astrid; Michel, Kerstin; Piyanova, Anastasia; Oppenheimer, Hannah; Dvir-Ginzberg, Mona; Rácz, Ildiko; Ulas, Thomas; Imbeault, Sophie; Bab, Itai; Schultze, Joachim L.; Zimmer, Andreas (June 2017). "A chronic low dose of Δ9-tetrahydrocannabinol (THC) restores cognitive function in old mice". Nature Medicine. 23 (6): 782–787. doi:10.1038/nm.4311. ISSN 1546-170X.
- ^ "Marijuana Reversed the Effects of Old Age in Mouse Brains". Inverse. 2017-05-08. Retrieved 2025-02-06.
- ^ "Only in Old Mice, a Touch of Cannabinoid Helps Memory | ALZFORUM". www.alzforum.org. Archived from the original on 2025-01-24. Retrieved 2025-02-06.
- ^ Albayram, Onder; Kondo, Asami; Mannix, Rebekah; Smith, Colin; Tsai, Cheng-Yu; Li, Chenyu; Herbert, Megan K.; Qiu, Jianhua; Monuteaux, Michael; Driver, Jane; Yan, Sandra; Gormley, William; Puccio, Ava M.; Okonkwo, David O.; Lucke-Wold, Brandon (2017-10-17). "Cis P-tau is induced in clinical and preclinical brain injury and contributes to post-injury sequelae". Nature Communications. 8 (1): 1000. Bibcode:2017NatCo...8.1000A. doi:10.1038/s41467-017-01068-4. ISSN 2041-1723. PMID 29042562.
External links
[edit]- Onder Albayram publications indexed by Google Scholar
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