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Weigert-Meyer Law

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The Weigert-Meyer Rule is a concept in urology and radiology that describes the anatomic relationship of two ureters in a duplicated renal collecting system, as well as the resulting patterns of hydronephrosis, obstruction, and reflux.[1]

In most cases, the upper renal moiety drains to the more medial ureteral orifice and the lower renal moiety tends to drain to the more lateral orifice.[2] The lower moiety often has a shorter muscular tunnel through the bladder wall due to the more lateral insertion, and is therefore more likely to reflux.[2] The upper moiety has higher risk of obstruction due to greater likelihood of ureterocele or ectopic insertion.[2][3][4]

This pattern was first described by German pathologist, Dr. Karl Weigert in 1877. This was further investigated by German pathologist, Dr. Robert Meyer, who described it as a "rule" in 1946.[2][3]

References

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  1. ^ El-Feky, Mostafa; Radswiki, The (2011-01-08), "Weigert-Meyer law", Radiopaedia.org, doi:10.53347/rID-12768, archived from the original on 2024-12-03, retrieved 2025-02-10
  2. ^ a b c d Meyer, Robert (1946). "Normal and abnormal development of the ureter in the human embryo; a mechanistic consideration". The Anatomical Record. 96 (4). PubMed: 355–371. doi:10.1002/ar.1090960403. PMID 20281492. Retrieved 22 January 2025.
  3. ^ a b Walizai, Tariq (31 October 2024). "Weigert-Meyer law". Radiopaedia.org. Online: Radiopaedia. Retrieved January 21, 2025.
  4. ^ Vergani, P; Locatelli, A (July 1, 1999). "Accuracy of prenatal ultrasonographic diagnosis of duplex renal system". Journal of Ultrasound in Medicine. 18 (7). Wiley: 463–467. doi:10.7863/jum.1999.18.7.463. PMID 10400048. Retrieved January 22, 2025.