User talk:Meodipt

This user is busy in real life and may not respond swiftly to queries.

first, the boiler-plate welcome:

Welcome!

Hello, Meodipt, and welcome to Wikipedia! Thank you for your contributions. I hope you like the place and decide to stay. Here are a few good links for newcomers:

I hope you enjoy editing here and being a Wikipedian! Please sign your name on talk pages using four tildes (~~~~); this will automatically produce your name and the date. If you need help, check out Wikipedia:Questions, ask me on my talk page, or place {{helpme}} on your talk page and someone will show up shortly to answer your questions. Again, welcome!

i'd also like to extend an invitation to the WikiProject on Psychedelics, Dissociatives and Deliriants. Which isn't invitation only or anything, i just thought that you might be interested in checking it out.

welcome again, hope you enjoy editing here!

Anti-aging claims

Medodipt - on my talk page, you said: "My main reason for adding pterostilbene to the "Anti-aging substances" category is that resveratrol is listed in this category, and pterostilbene is essentially identical in activity to resveratrol but with higher bioavailability. I refer you for instance to the following recent review articles; PMID 23808710 PMID 29168580 PMID 29210129 PMID 37979699. When I have time I may add a paragraph to the article citing these in support of this claim."

None of those sources qualifies as a valid source for health-related claims, as based on WP:MEDASSESS, top of left pyramid. Those sources are just exaggerated speculation extended from early-stage lab research, then published in low-quality, non-clinical and non-WP:MEDRS journals. Neither resveratrol nor pterostilbene has adequate clinical evidence to support an anti-aging or any health claim.

If there was adequate anti-aging evidence, there would be 1) a major systematic review in journals like The Lancet or New England Journal of Medicine, 2) a biotech drug candidate having completed rigorous Phase III trials with evidence of safety and efficacy, 3) a government (e.g., FDA) advisory for the public to consume more pterostilbene or resveratrol, or 4) national clinical organizations with dietary guidelines discussing #1-3.

None of these exist, despite 3+ decades of lab research. Take a dose of skepticism. Zefr (talk) 04:21, 24 January 2025 (UTC)[reply]

File:Olomorasib structure.png

Hi, for commons:File:Olomorasib structure.png on commons there is an error. The ring that contains nitrogen and oxygen actually has 8 atoms in it. There should be an extra carbon adjacent to the oxygen. It confused me as to whether Olomorasib was an oxazocine or oxazopine! cf the pubchem diagram. I hope you can fix it up! Graeme Bartlett (talk) 07:46, 6 March 2025 (UTC)[reply]

Oh dear yes will fix that. Teach me for trying to whip out a quick wiki page before work! Meodipt (talk) 08:12, 6 March 2025 (UTC)[reply]

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Anti-aging claims

File:Olomorasib structure.png