Draft:VIGICANCER
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VIGICANCER
[edit]VIGICANCER is a real-time surveillance system for childhood cancer outcomes embedded within the Population-Based Cancer Registry of Cali (RPCC), in Colombia. Established in 2009, it aims to monitor survival, relapse, treatment abandonment, and second malignancies among patients under the age of 19 diagnosed with cancer and treated in pediatric oncology units in Cali.
Purpose
[edit]Approximately 80% of childhood cancer cases occur in low- and middle-income countries (LMICs), where survival rates remain low. VIGICANCER was designed to systematically assess outcomes and guide interventions to improve clinical results, particularly in resource-constrained settings.
Development and Setting
[edit]VIGICANCER was developed through collaboration between pediatric oncologists and the RPCC at Universidad del Valle. It integrates features of a hospital-based registry with a population-based registry, allowing comprehensive data collection. Initial funding came from the Sanofi-Espoir Foundation through the My Child Matters program.
The system operates in Cali, a city of over 700,000 children and adolescents, but has expanded to include surveillance in ten additional major Colombian cities.
Methods
[edit]VIGICANCER collects baseline demographic and clinical information, and monitors events including death, relapse, treatment abandonment, and second malignancies. Data sources include medical records, hospital discharge logs, pathology reports, death certificates, and national insurance databases.
A rigorous quality assurance program was implemented, aiming for metrics such as >90% active follow-up, <10% loss to follow-up, and >95% death detection.
Results (2009–2013)
[edit]- **Patients enrolled**: 1,242 - **Age distribution**: 32% under 5 years old - **Gender**: 55% male - **Ethnicity**: 15% Afro-descendants - **Primary diagnoses**: Leukemias (ICCC group I predominant)
The five-year overall survival was: - 51.7% (95% CI, 47.9–55.4%) for children (<15 years) - 39.4% (95% CI, 29.8–50.5%) for adolescents (15–18.9 years) - 55.6% (95% CI, 48.5–62.2%) for acute lymphoblastic leukemia
Achievements
[edit]VIGICANCER has been internationally recognized, receiving awards from the International Society of Pediatric Oncology (SIOP) for its contributions to improving pediatric cancer care in LMICs.
It has been cited as a model surveillance system that demonstrates the feasibility and impact of integrating hospital-based and population-based cancer registries.
Expansion
[edit]Initially centered in Cali, VIGICANCER now operates in ten Colombian cities and is being considered for broader implementation. The project also led to the creation of the local foundation POHEMA to sustain ongoing operations.
See also
[edit]- Population-Based Cancer Registry of Cali
- Pediatric oncology
- Cancer epidemiology
- Public health surveillance
References
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