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Draft:Matteo Iannacone

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  • Comment: In accordance with Wikipedia's Conflict of interest policy, I disclose that I have a conflict of interest regarding the subject of this article. Frarro88 (talk) 09:21, 30 July 2025 (UTC)
Matteo Iannacone
Matteo Iannacone in 2024
Born
Milan, Italy
NationalityItalian
Alma materUniversity of Milan; Vita-Salute San Raffaele University; The Scripps Research Institute; Harvard Medical School
Known forImmune responses, viral immunopathology
AwardsArmenise-Harvard Career Development Award, ERC Starting Grant, EMBO Young Investigator Award
Scientific career
FieldsImmunology, Pathology
InstitutionsSan Raffaele Scientific Institute
Academic advisorsLuca Guidotti, Francis V. Chisari, Ulrich von Andrian

Matteo Iannacone is an Italian immunologist and professor of pathology. He is director of the Division of Immunology, Transplantation and Infectious Diseases at the San Raffaele Scientific Institute in Milan, Italy.[1]

Education

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Iannacone received his medical degree from the University of Milan in 2001 and completed a residency in internal medicine in 2007.[2] He obtained a PhD in immunology from Vita-Salute San Raffaele University in 2011.[3]

Career

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He conducted postdoctoral research at The Scripps Research Institute and Harvard Medical School, working with Luca Guidotti, Francis V. Chisari and Ulrich von Andrian.[4] In 2010 he established his laboratory at the San Raffaele Scientific Institute, where he became division director in 2023 and full professor at Vita-Salute San Raffaele University in 2024.[1]

Research

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Iannacone’s work focuses on immune responses to viral infections and liver immunopathology. His studies have examined platelet-mediated cytotoxicity in viral hepatitis,[5] the role of subcapsular sinus macrophages in neurotropic virus infections,[5] and the dynamics of CD8⁺ T cells during hepatic priming.[6] He has also published research on spatial immune niches and interleukin-2–based immunotherapies.[7]

Awards and honors

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He has received several awards, including the Armenise-Harvard Career Development Award (2010), the ERC Starting Grant (2011), the EMBO Young Investigator Award (2016) and the ERC Advanced Grant (2024).[8] He is an elected member of the European Molecular Biology Organization and the Henry Kunkel Society.[9]

Selected publications

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  • Platelets mediate cytotoxic T lymphocyte-induced liver damage. Nature Medicine (2005)
  • Subcapsular sinus macrophages prevent CNS invasion on peripheral infection with a neurotropic virus. Nature (2010)
  • Immunosurveillance of the liver by intravascular effector CD8+ T cells. Cell (2015)
  • Dynamics and genomic landscape of CD8+ T cells undergoing hepatic priming. Nature (2019)
  • CD8 cis-targeted IL-2 drives antiviral activity against hepatitis B virus. Science Translational Medicine (2024)

References

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  1. ^ a b "Matteo Iannacone - HSR Research". research.hsr.it.
  2. ^ "Iannacone Matteo". www.unisr.it.
  3. ^ "UniSR - UNIFIND - IANNACONE MATTEO". unifind.unisr.it.
  4. ^ "Fuga dei cervelli e rimpatri: Matteo Iannacone, l'esempio di un ritorno importante per il Paese". January 23, 2024.
  5. ^ a b Guglielmi, Giorgia (November 21, 2020). "I laboratori italiani si reinventano contro la pandemia". Nature Italy. doi:10.1038/d43978-020-00027-w – via www.nature.com.
  6. ^ "Epatite B, al San Raffaele sperimentata per la prima volta al mondo una molecola immunoterapica". Osservatorio Malattie Rare. January 28, 2024.
  7. ^ "Nuovo ERC a Matteo Iannacone". www.hsr.it.
  8. ^ "2 ricercatori del San Raffaele vincono 2 ERC Advanced Grants". www.hsr.it.
  9. ^ "Matteo Iannacone dell'Ospedale San Raffaele tra i migliori ricercatori europei under 40 - insalutenews.it". October 26, 2015.
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