This is an image of murine CTLA4 (CD152) which is necessary for inhibiting the T cells. It binds to CD28 with a higher affinity than the costimulatory molecules CD80 and CD86. This image is derived from Protein Data Bank data 1DQT which was published by Ostrov et al. in 2000. I rendered the image in PyMol myself based on the published pdb file.

For the published pdb, please see: Ostrov, D.A., Shi, W., Schwartz, J.C., Almo, S.C., Nathenson, S.G. Structure of murine CTLA-4 and its role in modulating T cell responsiveness. Science v290 pp.816-819 , 2000.

DescriptionCTLA4 Crystal Structure.rsh.png	Crystal structure of CTLA4 as published in the Protein Data Bank (PDB: 1DQT)
Date	12 October 2006
Source	Created from PDB 1DQT and rendered by me using Pymol
Author	Ramin Herati
Permission (Reusing this file)	Public domainPublic domainfalsefalse I, the copyright holder of this work, release this work into the public domain. This applies worldwide. In some countries this may not be legally possible; if so: I grant anyone the right to use this work for any purpose, without any conditions, unless such conditions are required by law.