^ abDinamo Minsk played their home matches at OSK Brestskiy, Brest, instead of their temporary stadium Traktor Stadium, Minsk.
^AEK Larnaca played their home match at Antonis Papadopoulos Stadium, Larnaca, instead of their regular stadium GSZ Stadium, Larnaca.
^Spartak Trnava played their home matches at Štadión FC ViOn, Zlaté Moravce, instead of their regular stadium Štadión Antona Malatinského, Trnava, due to renovation.[3]
^Sampdoria played their home match at Stadio Olimpico, Turin, instead of their regular stadium Stadio Luigi Ferraris, Genoa, due to works on the playing surface.[4]
^The match was abandoned in the 52nd minute with a 2–1 lead for Legia Warsaw after a Legia Warsaw player was hit in the head by an object thrown from the crowd. On 4 August 2015, UEFA awarded Legia Warsaw with a 3–0 win against Kukësi[1][5] Kukësi were given a €70,000 fine and ordered to play their next home match behind closed doors.[6]
^Kukësi played their home matches at Qemal Stafa National Stadium, Tirana, instead of their regular stadium Zeqir Ymeri Stadium, Kukës.
^""Qəbələ" UEFA-dan faks aldı" [Gabala received a fax from UEFA] (in Azerbaijani). Futbolinfo.az. 15 July 2015. Archived from the original on 24 July 2015. Retrieved 24 July 2015.
Note: Between the 1999–2000 and 2008–09 seasons, the competition was still known as the UEFA Cup. All seasons are included following the competition's absorption of the Cup Winners' Cup.